Rejuran (Rejuran Healer) Complete Guide — What to Know Before You Get It in Korea

Rejuran: Who It Suits / Who It Doesn't

Rejuran is a skin booster in which DNA fragments extracted and purified from salmon (polynucleotide, PN) are injected in small amounts into the shallow layers of the skin. Unlike fillers, which change the shape of the face, it aims to support a better environment for tired, thinning skin to recover, gradually improving skin texture, fine lines and firmness, which is why it is also called a "regeneration injection."

• You have thin, sensitive skin that flushes easily or doesn't hold makeup well
• You are bothered by fine lines around the eyes and cheeks, or dull, rough skin texture
• You get laser treatments often and want to support your skin's recovery as well
• You want to improve your overall skin condition along with shallow pores and scars
• You want to prepare your skin starting a few weeks before an important event such as a wedding or photo shoot

How It Works — Why Results Take a Few Weeks to Show

PN is a fragment of DNA that is known to help create the environment damaged skin tissue needs to recover. Unlike hyaluronic acid (water-glow injections), which hydrates right away, it takes time for the skin to repair itself, so rather than changing immediately after treatment, many people notice gradual changes in skin texture and moisture from about 2–4 weeks onward.

• Main ingredient: salmon-derived PN (polynucleotide)
• Injection depth: the shallow layer of the skin (dermis), in small, closely spaced amounts
• Expected changes: skin texture, fine lines, skin thickness, firmness and radiance (varies by person)
• Other products use similar PN or PDRN ingredients, with slightly different concentrations and uses.

Product Line — Rejuran Healer vs. Eye vs. HB

Under the "Rejuran" name, several products are divided by purpose. The product names used may differ slightly by clinic and over time, so be sure to ask during your consultation which product will be used.

Injection Method — Hand Injection vs. Device Injection

Neither is better in general; the choice depends on the area and purpose. Many clinics use a device for the whole face and hand injection for delicate areas such as around the eyes and nasolabial folds. If your trip is short, ask about a method that makes the bumps less noticeable.

Treatment Day — Step by Step and Pain

1. 1
   Check-in and consultation (about 20 minutes): The doctor looks at your skin and concerns and decides the product, amount and injection method. Your manager interprets.
2. 2
   Cleansing and numbing cream (30–40 minutes): Numbing cream is applied to the whole face.
3. 3
   Product checkYou confirm the box, label and volume of the product in front of you before it is opened.
4. 4
   Treatment (15–30 minutes)Small amounts are injected across the whole face by hand or with a device.
5. 5
   Soothing (about 15 minutes)Cooling or a calming mask settles redness and warmth.
6. 6
   Heading homeYou will have bumps and redness, so bring a mask and a hat to be comfortable.

Bumps and Downtime — Recovery Timeline

"Bumps" are small raised marks that form where the product sits at each injection site. Rejuran bumps are more noticeable than with other skin boosters, but most settle within a day or two.

• Treatment day
  Bumps and redness at each injection site. More noticeable with hand injection.
• Days 1–2
  Most bumps settle. Faint needle marks may remain.
• Around day 3
  Mostly coverable with makeup. If you have bruising, it begins to fade from this point.
• Week 1
  Bruises, if any, fade to yellow. Your skin starts to feel more hydrated.
• After weeks 2–4
  Changes in skin texture, fine lines and firmness appear gradually. This is when you schedule the next session.

When Results Show, and How Many Sessions at What Interval?

Some people notice a change in skin texture after just one session, but Rejuran works best as sessions build up. Injecting a large amount at once does not make results come faster.

Sample Trip Schedule — When Is the Best Time to Get It?

4 days / 3 nights (1 Rejuran session)

• Day 1
  Arrive → consultation → treatment. You'll have bumps, so keep dinner light at your hotel
• Day 2
  Bumps settle; light sightseeing is fine. Avoid saunas and alcohol
• Day 3
  Makeup is possible for most people. Photos are more comfortable from this point.
• Day 4
  Check-up before departure → aftercare instructions for back home

• If possible, get it early in your trip. If you get it right before leaving, you may board the plane with bumps and bruising still showing, or find it hard to have the clinic check you if something is wrong.
• Most people can fly home the next day, but allowing 2–3 days is more comfortable given the bumps and bruising. Cabin air is dry, so reapply moisturizer.
• If you have an event where photos matter, such as a wedding or photo shoot, it's best to have the treatment at least 2–4 weeks before.
• If you plan several sessions, fixing the date of your next visit 2–4 weeks later in advance keeps your course on track.

How to Check It's Genuine (Be Sure to Check)

Rejuran goes directly into the skin, so confirming that the product is genuine and the amount is correct is important. Popular products can have look-alikes with similar names or packaging, so feel free to make the requests below.

1. Before treatment, check the product name (Rejuran Healer, Rejuran Eye, Rejuran HB, etc.) and volume (ml/cc) on the box and label.
2. Rejuran usually comes in a syringe. Check that a new, sealed product is opened in front of you.
3. Also check the lot number (manufacturing number) and expiry date on the label, and the authenticity label or serial number if there is one.
4. Ask how many units (how many cc) will be used, and if it is mixed with other products, what is added and how much.
5. After the treatment, you can ask to see the empty syringe and label.

Aftercare and Warning Signs

Aftercare

• Skip makeup on the treatment day, and from the next day apply it lightly with gentle products.
• Do not rub or massage the injected area. The bumps will settle on their own.
• For 2–3 days, avoid saunas, jjimjilbang, hot baths, alcohol and strenuous exercise.
• For about a week, pause exfoliation, peels and retinol products, and moisturize generously.
• Apply sunscreen carefully, and use a hat or parasol while sightseeing.

When to Contact Your Manager Right Away

• Redness, swelling or pain that keeps getting worse after several days
• The injection site is hot, produces pus, or you develop a fever
• Itching, hives, a tight feeling in the chest or other signs of a possible allergy
• A hard lump that grows or stays for a long time

Treatments Often Combined

Questions to Ask at Your Consultation · How to Choose a Clinic

Good Questions to Ask at Your Consultation

1. Which Rejuran product suits my skin — Healer, Eye or HB — and why?
2. How many cc will be used, and will it be by hand or device?
3. Can I see the product opened, check the label and lot number, and check the empty syringe afterward?
4. Will the doctor perform the treatment personally?
5. How many days of bumps and bruising should I expect? Will it interfere with my travel plans?
6. How many sessions do I need, and when should I have the next one after returning home?

What to Look for in a Clinic

• Does the doctor examine your skin in person and choose the product to suit each area?
• Does the clinic explain product name, amount and injection method openly, and agree to authenticity checks?
• Does it avoid recommending more volume, combinations or sessions than necessary?
• Can they communicate in your language, and will they check your progress by photo after you return home?

KBEAU connects you with partner dermatology clinics in Gangnam and Apgujeong. Send us a photo of your face and we will tell you in advance whether Rejuran suits you, which product and method are best, and the right timing for your travel schedule. On the day of treatment, a dedicated manager accompanies you to interpret and help with the authenticity check. We can also arrange accommodation near the clinic and airport pickup.